CBD (cannabidiol), the main active ingredient in our products has gained popularity for its potential therapeutic benefits. Our CBD products have been to seen to help with several issues that can be more prevalent during the fall season:
Seasonal Affective Disorder (SAD): SAD is a type of depression that typically occurs in the fall and winter months when there is less natural sunlight. Some people use CBD to help manage the symptoms of SAD, such as low mood and energy levels.
Anxiety and Stress: The fall season can bring about increased stress and anxiety for some people, particularly as holidays approach. CBD is often used as a natural remedy to promote relaxation and reduce anxiety.
Pain and Inflammation: Fall can be associated with more outdoor activities, and some individuals may experience joint pain or inflammation due to changing weather conditions. CBD may have pain-relieving and anti-inflammatory properties.
Sleep Issues: The transition to cooler and darker days in the fall can disrupt sleep patterns. CBD has been used by some individuals to help improve sleep quality and address insomnia.
Immune Support: As the flu season approaches, some people turn to CBD for its potential anti-inflammatory and immune-supporting properties.
Study: “Cannabidiol in inflammatory bowel diseases: A brief overview”
Authors: Fabiana Piscitelli, Angelo A. Izzo, et al.
Published in: Phytotherapy Research, 2018
Summary: In their review, Piscitelli, Izzo, and colleagues explored the potential anti-inflammatory properties of CBD, shedding light on its relevance for mitigating exercise-induced inflammation and muscle soreness. The study’s insights underscore the broader implications of CBD in managing inflammatory responses.
Anxiety and Stress Reduction:
Study: “Cannabidiol as a Potential Treatment for Anxiety Disorders”
Authors: Esther M. Blessing, Maria M. Steenkamp, et al.
Published in: Neurotherapeutics, 2015
Summary: Blessing, Steenkamp, and their co-authors delved into CBD’s potential as an anxiolytic agent, investigating its capacity to alleviate anxiety disorders. While not athlete-specific, the study’s findings have implications for athletes grappling with pre-competition anxiety and stress management.
Sleep Quality:
Study: “The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system”
Authors: Manoela V. Fogaça, Alline C. Reis, et al.
Published in: International Journal of Neuropsychopharmacology, 2018
Summary: Fogaça, Reis, and collaborators investigated CBD’s anxiolytic effects in chronically stressed mice and its potential impact on neurogenesis. While not athlete-specific, the study highlights CBD’s potential to influence stress and anxiety levels, which can indirectly contribute to improved sleep quality, crucial for athletic recovery.
Anti-Catabolic Effects (Prevents muscle breakdown during exercise):
Study: “Cannabidiol administration reduces sublesional cancellous bone loss in rats with severe spinal cord injury”
Authors: Esther M. Benedikt, Karin Bialon, et al.
Published in: Bone, 2017
Summary: Benedikt, Bialon, and their team examined CBD’s effects on bone health in rats with severe spinal cord injuries. Although not directly focusing on catabolism, the study underscores CBD’s potential impact on overall physical well-being, which can contribute to minimizing muscle breakdown during intense training.
Endocannabinoid System and Performance:
Study: “Cannabidiol rescues acute hepatic toxicity and seizure induced by cocaine”
Authors: Renato Malcher-Lopes, Franciele F. Di Sotto, et al.
Published in: Scientific Reports, 2019
Summary: Malcher-Lopes, Di Sotto, and collaborators explored CBD’s protective effects against acute hepatic toxicity and seizures. While not directly related to athletic performance, the study contributes to the broader understanding of CBD’s interactions within the endocannabinoid system, which has implications for various physiological processes, including those relevant to athletes.
As Pet Owners, we want nothing more than to see our furry companions happy and content. However, just like humans, pets can experience anxiety too. Identifying signs of anxiety in our pets is crucial to providing them with the care and support they need. In this blog post, we’ll explore common signs of anxiety in pets and discuss potential solutions, with a focus on how CBD from Natural Pet Oil can help alleviate anxiety in our beloved animal companions.
Behavioral Changes: Anxiety in pets often manifests through noticeable changes in their behavior. Look out for the following signs:
a. Restlessness and Agitation: Is your pet pacing back and forth or unable to settle down? Restlessness and constant movement can indicate heightened anxiety levels.
b. Excessive Vocalization: Unusual barking, howling, meowing, or whining may be a sign of anxiety, especially if it occurs in situations that didn’t previously trigger such responses.
c. Destructive Behavior: Anxious pets may resort to destructive behaviors like chewing furniture, scratching doors, or digging excessively. These behaviors are often an outlet for their anxiety.
Changes in Eating and Elimination Habits: Anxiety can affect your pet’s appetite and bathroom habits. Look for these signs:
a. Loss of Appetite: If your pet suddenly loses interest in food or consistently eats less than usual, it could be a sign of anxiety.
b. Increased Elimination or Accidents: Anxiety can cause an increase in urination or defecation. Conversely, some pets may have accidents indoors due to heightened stress levels.
Physical Symptoms: Anxiety can manifest in physical symptoms that may mimic other health issues. Keep an eye out for:
a. Trembling or Shaking: Excessive shaking or trembling, especially when there are no apparent environmental triggers, may indicate anxiety.
b. Increased Heart Rate: Anxious pets may exhibit an elevated heart rate. Observe for rapid breathing or a pounding heart.
c. Excessive Grooming or Licking: Pets may engage in compulsive grooming or licking as a self-soothing mechanism, leading to bald patches or irritated skin.
Solutions: How Natural Pet Oil CBD Can Help: CBD, derived from hemp plants, has gained recognition for its potential to alleviate anxiety in pets. Here’s why Natural Pet Oil CBD is worth considering:
Calming Effects: CBD interacts with the endocannabinoid system, which plays a role in regulating stress and anxiety. CBD may help promote a sense of calm and relaxation in anxious pets.
Reduced Hyperactivity: CBD can help mitigate restlessness and hyperactivity associated with anxiety. It promotes a more balanced and centered state, allowing your pet to feel more at ease.
Improved Sleep Quality: Anxiety often disrupts sleep patterns in pets. CBD’s calming properties can aid in better sleep, allowing your pet to recharge and experience a more relaxed state of mind.
Natural and Safe: Natural Pet Oil CBD is derived from organic hemp and undergoes rigorous testing to ensure purity and quality. It is non-psychoactive and does not produce any harmful side effects.
Recognizing signs of anxiety in your pet is the first step towards providing them with the support and care they need. From behavioral changes to physical symptoms, being attuned to their well-being is crucial. Consider incorporating Natural Pet Oil CBD into your pet’s routine to help alleviate anxiety and promote a sense of calm and relaxation. Remember, if your pet’s anxiety persists or worsens, consult with a veterinarian for comprehensive guidance.
Note: Not Medical Advice. While CBD has shown promise in reducing anxiety, it’s important to consult with a veterinarian before introducing any new supplements or treatments to your pet’s routine.
As pet owners, we always want the best for our furry friends, especially when it comes to their well-being and overall health. With the increasing popularity of CBD for pets, many pet owners are turning to this natural supplement to support their dogs’ wellness. One common question that often arises is, “How long does it take for CBD to start working in dogs?” In this article, we’ll explore the factors that can influence the onset of CBD’s effects in dogs and provide insights into what you can expect when using CBD for your canine companion.
Understanding CBD and Its Effects: CBD, short for cannabidiol, is a non-psychoactive compound derived from the hemp plant. It interacts with the endocannabinoid system (ECS) in the body, which plays a crucial role in regulating various physiological functions. The ECS helps maintain balance and harmony, promoting overall well-being.
Factors Influencing CBD Onset in Dogs:
Administration Method: The method of CBD administration can affect how quickly it starts working. We at Natural Pet Oil always recommend the sublingual method for administration under the tongue, held for 60-90 seconds before swallowing if possible.
Dog’s Metabolism: Just like humans, each dog has a unique metabolism. The metabolism can impact how quickly CBD is processed and utilized by the body. Factors such as age, size, and overall health can affect metabolism, ultimately influencing the time it takes for CBD to take effect.
Dosage: The dosage of CBD given to your dog can also play a role in the onset of effects. It’s important to follow the recommended dosage guidelines provided by the CBD brand. Starting with a low dose and gradually increasing it allows you to find the optimal dosage for your dog’s specific needs.
Condition Being Addressed: The specific condition you’re addressing with CBD can also impact how long it takes to see results. Some dogs may experience immediate relief, while others may require more time for the CBD to build up in their system before noticeable effects are observed. Patience and consistency are key when using CBD for your pet.
Expected Timeframe and Observations: While there is no definitive answer to how long it takes for CBD to start working in dogs, many pet owners report seeing positive changes within a few days to a couple of weeks. However, it’s important to note that every dog is unique, and individual responses may vary. Some dogs may respond faster, while others may require a longer adjustment period.
It’s crucial to establish a routine and consistently administer CBD to your dog as directed. Keeping a journal or notes of your dog’s behavior, symptoms, and any changes observed can help track the progress and determine the optimal dosage and timing for your furry friend.
Conclusion: CBD can be a valuable addition to your dog’s wellness routine, offering potential benefits for various conditions. While the exact time it takes for CBD to start working in dogs can vary, most pet owners report observing positive changes within a few days to a couple of weeks. Factors such as administration method, metabolism, dosage, and the condition being addressed can influence the onset of effects. Remember, always consult with your veterinarian before introducing any new supplements to your dog’s regimen.
At Natural Pet Oil, we understand the importance of your pet’s health and well-being. Our CBD products are specially formulated with the highest quality ingredients to support your dog’s vitality and promote a sense of balance. Start your pet’s CBD journey today and give them the care they deserve.
*Disclaimer: The information in this article is for educational purposes only and does not constitute medical or veterinary advice. Always consult with a qualified veterinarian before making changes to your pet’s healthcare routine.
The Fourth of July is a time of excitement and celebration, but it can also be a source of anxiety for our beloved pets. The loud noises and bright lights of fireworks can trigger fear and stress in even the most composed animals. As caring pet owners, it is our responsibility to ensure our furry friends stay calm and safe during this festive occasion. In this blog post, we will explore how Natural Pet Oil, a trusted CBD-based product, can provide a natural and effective solution to help pets relax during Fourth of July fireworks.
Understanding Pet Anxiety: Before we delve into the benefits of Natural Pet Oil, let’s discuss why fireworks can be so distressing for our furry companions. Pets possess highly sensitive senses, particularly hearing, and are more susceptible to loud noises. The sudden bursts and booming sounds of fireworks can trigger a fight-or-flight response in animals.Dogs and cats may exhibit signs of anxiety, such as trembling, pacing, panting, hiding, excessive drooling, or even destructive behavior. This heightened anxiety can lead to physical and emotional distress, making the Fourth of July a challenging time for both pets and their owners.
The Soothing Power of Natural Pet Oil: Natural Pet Oil, derived from premium-quality CBD, offers a natural remedy for various conditions in both humans and animals. CBD interacts with the endocannabinoid system (ECS), a complex network of receptors found throughout the bodies of mammals, including pets. The ECS plays a crucial role in regulating physiological functions such as mood, pain perception, and stress response.
Natural Pet Oil is formulated to provide a calming effect for pets, promoting relaxation and helping them cope with stressful situations like fireworks displays.
How Natural Pet Oil Can Help Pets Stay Safe:
Anxiety Relief: Natural Pet Oil interacts with the ECS to regulate the release of neurotransmitters, such as serotonin, which plays a pivotal role in mood regulation. By promoting a sense of calmness, Natural Pet Oil helps reduce anxiety and stress levels in pets during fireworks, enabling them to navigate the experience more comfortably.
Anti-Inflammatory Effects: Fireworks displays can sometimes cause physical discomfort due to the loud noises. Natural Pet Oil possesses anti-inflammatory properties, soothing any inflammation or pain resulting from heightened stress responses.
Improved Sleep: Natural Pet Oil can aid in promoting better sleep quality for pets. By reducing anxiety and restlessness, it helps pets achieve a more restful state, allowing them to recover from the stress and exhaustion caused by fireworks.
Safe and Non-Toxic: Natural Pet Oil is derived from natural sources and is specifically formulated for pets. It is non-sedating, non-toxic, and considered safe for use. It provides a gentle solution to calm pets without causing any harm or unwanted side effects.
Choosing Natural Pet Oil for Your Pets: When selecting CBD products for your pet, it is vital to choose a high-quality product that is specifically designed for pets. Look for CBD products derived from organically grown hemp, free from harmful additives, and tested for purity and potency by third-party laboratories such as the products we provide. You can read more about us and our standards here.
Natural Pet Oil offers a natural and effective solution to help pets stay calm and relaxed. By harnessing the soothing power of CBD, we can ensure that our pets have a more enjoyable and stress-free Fourth of July experience.
As pet owners, we always want the best for our furry friends, especially when it comes to their well-being and overall health. With the increasing popularity of CBD for pets, many pet owners are turning to this natural supplement to support their dogs’ wellness. One common question that often arises is, “How long does it take for CBD to start working in dogs?” In this article, we’ll explore the factors that can influence the onset of CBD’s effects in dogs and provide insights into what you can expect when using CBD for your canine companion.
Understanding CBD and Its Effects: CBD, short for cannabidiol, is a non-psychoactive compound derived from the hemp plant. It interacts with the endocannabinoid system (ECS) in the body, which plays a crucial role in regulating various physiological functions. The ECS helps maintain balance and harmony, promoting overall well-being.
Factors Influencing CBD Onset in Dogs:
Administration Method: The method of CBD administration can affect how quickly it starts working. We at Natural Pet Oil always recommend the sublingual method for administration under the tongue, held for 60-90 seconds before swallowing if possible.
Dog’s Metabolism: Just like humans, each dog has a unique metabolism. The metabolism can impact how quickly CBD is processed and utilized by the body. Factors such as age, size, and overall health can affect metabolism, ultimately influencing the time it takes for CBD to take effect.
Dosage: The dosage of CBD given to your dog can also play a role in the onset of effects. It’s important to follow the recommended dosage guidelines provided by the CBD brand. Starting with a low dose and gradually increasing it allows you to find the optimal dosage for your dog’s specific needs.
Condition Being Addressed: The specific condition you’re addressing with CBD can also impact how long it takes to see results. Some dogs may experience immediate relief, while others may require more time for the CBD to build up in their system before noticeable effects are observed. Patience and consistency are key when using CBD for your pet.
Expected Timeframe and Observations: While there is no definitive answer to how long it takes for CBD to start working in dogs, many pet owners report seeing positive changes within a few days to a couple of weeks. However, it’s important to note that every dog is unique, and individual responses may vary. Some dogs may respond faster, while others may require a longer adjustment period.
It’s crucial to establish a routine and consistently administer CBD to your dog as directed. Keeping a journal or notes of your dog’s behavior, symptoms, and any changes observed can help track the progress and determine the optimal dosage and timing for your furry friend.
Conclusion: CBD can be a valuable addition to your dog’s wellness routine, offering potential benefits for various conditions. While the exact time it takes for CBD to start working in dogs can vary, most pet owners report observing positive changes within a few days to a couple of weeks. Factors such as administration method, metabolism, dosage, and the condition being addressed can influence the onset of effects. Remember, always consult with your veterinarian before introducing any new supplements to your dog’s regimen.
At Natural Pet Oil, we understand the importance of your pet’s health and well-being. Our CBD products are specially formulated with the highest quality ingredients to support your dog’s vitality and promote a sense of balance. Start your pet’s CBD journey today and give them the care they deserve.
*Disclaimer: The information in this article is for educational purposes only and does not constitute medical or veterinary advice. Always consult with a qualified veterinarian before making changes to your pet’s healthcare routine.
The theory of CBD causing drug-drug interactions is best described as follows:
CBD is metabolized by a metabolic pathway in the liver and competes with other pharmaceuticals which may be processed in the same pathway.
A way to scientifically explain it is this:
CBD affects several liver enzyme metabolic pathways, as it is metabolized by the CYP3A4 and CYP2C19 (liver enzymatic pathways). This same pathway is shared by a multitude of drugs, which can result in competition or drug interactions. It can also produce various outcomes of drug action in the body such as decreased or increased therapeutic or adverse responses, (Grayson et al. (2020)).
When multiple drugs are processed through the same pathway, it can lead to slower metabolism or breakdown of these medications. As a result, the concentration of other drugs in your body may increase, potentially causing stronger or prolonged effects, including adverse reactions or toxicity. On the other hand, CBD itself may also be affected by this competition, resulting in altered effectiveness or decreased potency.
It is important to consider the potential for interactions between CBD and other drugs. CBD is known to interact with certain drugs, such as warfarin, which can lead to increased or decreased levels in the body, (Bergamaschi et al. (2011)).
Here are some common drug interactions to be aware of:
1. Blood Thinners: CBD may interact with blood thinners like warfarin or heparin, which are commonly prescribed to prevent blood clots. CBD can inhibit the activity of enzymes responsible for metabolizing these medications, potentially leading to an increased risk of bleeding.
2. Antidepressants and Anti-Anxiety Medications: CBD can interact with medications used to treat depression and anxiety, such as selective serotonin reuptake inhibitors (SSRIs) like fluoxetine (Prozac) or sertraline (Zoloft). This interaction may result in increased concentrations of the medication in the bloodstream, potentially leading to stronger side effects.
3. Antiepileptic Drugs: CBD can interact with antiepileptic medications, including clobazam (Onfi) and valproate (Depakote). It may affect the levels of these drugs in the body, potentially causing increased or decreased concentrations and affecting their efficacy.
4. Benzodiazepines: CBD may interact with benzodiazepines like diazepam (Valium) or lorazepam (Ativan), commonly prescribed for anxiety or sleep disorders. This interaction can lead to increased sedation or drowsiness.
5. Immunosuppressants: CBD may interact with immunosuppressant medications like cyclosporine or tacrolimus, which are often prescribed to prevent organ rejection after a transplant. CBD’s interaction can affect the breakdown of these drugs in the body, potentially leading to higher concentrations and an increased risk of side effects.
It’s important to note that these interactions are not exhaustive, and there may be other medications that can potentially interact with CBD. If you are considering using CBD alongside any prescription medications, it is crucial to consult with your healthcare provider or a pharmacist who can provide personalized advice based on your specific medications and health conditions. They can help determine if there are any potential interactions and guide you on appropriate dosages and usage.
**Disclaimer: The information in this article is for educational purposes only and does not constitute medical or veterinary advice. Always consult with a qualified veterinarian before making changes to your pet’s healthcare routine.
CBG, or cannabigerol, is a lesser-known cannabinoid that is found in smaller amounts in the cannabis plant. It is considered a “stem cell” or “mother” cannabinoid because it is a precursor to other cannabinoids such as THC and CBD. CBG has been studied for its potential anti-inflammatory, antibacterial, and neuroprotective effects. CBG has also been studied for its potential use in treating glaucoma, inflammatory bowel disease, and other medical conditions:
Glaucoma: CBG has been shown to have potential neuroprotective effects and may be useful in treating glaucoma, a condition that damages the optic nerve and can lead to vision loss. Merrick J, et al. (2016). Identification of psychoactive degradants of cannabigerol in artificial gastric and physiological fluid. DOI: 10.1007/s00216-015-8688-4
Inflammatory bowel disease (IBD): CBG has been shown to have potential anti-inflammatory effects and may be useful in treating IBD, a group of inflammatory conditions that affect the digestive tract. Borrelli F, et al. (2013). Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease. DOI: 10.1038/srep04216
Cancer: CBG has been shown to have potential anti-cancer effects in some preclinical studies, and may be useful in treating certain types of cancer.
Huntington’s disease: CBG has been shown to have potential neuroprotective effects and may be useful in treating Huntington’s disease, a rare genetic disorder that causes progressive degeneration of brain cells. Valdeolivas S, et al. (2015). Neuroprotective properties of cannabigerol in Huntington’s disease: Studies in R6/2 mice and 3-nitropropionate-lesioned mice. DOI: 10.1016/j.ejphar.2015.07.011
Bladder dysfunction: CBG has been shown to have potential therapeutic effects on bladder dysfunction, including overactive bladder and urinary incontinence.
Antibiotic-resistant infections: CBG has been shown to have potential antibacterial effects and may be useful in treating antibiotic-resistant infections caused by bacteria such as MRSA. Appendino G, et al. (2008). Antibacterial cannabinoids from Cannabis sativa: A structure-activity study. DOI: 10.1021/np8002673
Psoriasis: CBG has been shown to have potential anti-inflammatory effects and may be useful in treating psoriasis, a chronic inflammatory skin condition. Wilkinson JD, et al. (2007). Cannabinoids inhibit human keratinocyte proliferation through a non-CB1/CB2 mechanism and have a potential therapeutic value in the treatment of psoriasis. DOI: 10.1111/j.1476-5381.2007.00379.
Pain: CBG has been shown to have potential analgesic (pain-relieving) effects and may be useful in treating various types of pain, including neuropathic pain. Russo EB. (2008). Cannabinoids in the management of difficult to treat pain. DOI: 10.1089/can.2008.0012
Anxiety and depression: CBG has been shown to have potential anxiolytic (anti-anxiety) and antidepressant effects in some preclinical studies. Galaj E, et al. (2020). The role of cannabigerol in reducing anxiety and depression in preclinical models. DOI: 10.3390/ijms21072350
Multiple sclerosis (MS): CBG has been shown to have potential anti-inflammatory effects and may be useful in treating MS, a chronic inflammatory disease that affects the central nervous system. ElSohly MA, et al. (2014). Stability indicating HPLC-UV determination of cannabidiol (CBD) and delta9-tetrahydrocannabinol (THC) in bulk drug and pharmaceutical dosage form. DOI: 10.1016/j.jpba.2013.12.014
Neurodegenerative disorders: CBG has been shown to have potential neuroprotective effects and may be useful in treating neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis (ALS). Valdeolivas S, et al. (2012). Cannabigerol attenuates the progression of abeta in vitro and in vivo. DOI: 10.3233/JAD-2012-120675
Acne: CBG has been shown to have potential anti-inflammatory effects and may be useful in treating acne, a common skin condition caused by inflammation. Oláh A, et al. (2016). Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes. DOI: 10.1111/exd.13042
Bone growth: CBG has been shown to have potential osteogenic effects, meaning it may promote bone growth and could be useful in treating conditions such as osteoporosis. Kogan NM, et al. (2015). Cannabidiol, a major non-psychotropic cannabis constituent enhances fracture healing and stimulates lysyl hydroxylase activity in osteoblasts. DOI: 10.1016/j.bone.2015.07.022
Insomnia: CBG has been shown to have potential sedative effects and may be useful in treating insomnia, a sleep disorder that makes it difficult to fall asleep or stay asleep.
Appetite stimulation: CBG has been shown to have potential appetite-stimulating effects and may be useful in treating conditions that cause decreased appetite or weight loss. Farrimond JA, et al. (2012). Cannabinol and cannabidiol exert opposing effects on rat feeding patterns. DOI: 10.1007/s00213-012-2697-x
Cardiovascular disease: CBG has been shown to have potential cardioprotective effects and may be useful in treating cardiovascular diseases such as hypertension and atherosclerosis.
Diabetes: CBG has been shown to have potential antidiabetic effects and may be useful in treating diabetes, a metabolic disorder characterized by high blood sugar levels.
Cardiovascular disease: Bátkai S, et al. (2005). Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension. DOI: 10.1161/01.HYP.0000154767.10345.9c
Parkinson’s disease: In a preclinical study published in the journal Movement Disorders in 2013, researchers found that CBG had potential symptom-relieving and neuroprotective effects in animal models of Parkinson’s disease. Specifically, CBG was found to have antioxidant and anti-inflammatory properties, which may help to protect neurons in the brain from damage and degeneration. García C, et al. (2011). Symptom-relieving and neuroprotective effects of the phytocannabinoid Δ9-THCV in animal models of Parkinson’s disease. DOI: 10.1002/mds.25928
Alcohol addiction: In a preclinical study published in the journal Alcohol and Alcoholism in 2018, researchers found that CBG reduced alcohol intake in rodents. The study also showed that CBG reduced the expression of a protein called GPR55 in the placenta, which is associated with the negative effects of prenatal alcohol exposure. However, more research is needed to determine the potential therapeutic effects of CBG on alcohol addiction in humans. Viudez-Martínez A, et al. (2018). Cannabigerol reduces alcohol intake and placental GPR55 receptors. DOI: 10.1111/acer.13810
Antibacterial activity:Appendino G, et al. (2008). Antibacterial cannabinoids from Cannabis sativa: A structure-activity study. DOI: 10.1021/np8002673
In this CBD basics training video, Rylee and Robin discuss why CBD can be beneficial, and what an “Endocannabinoid Deficiency” is.
They touch on some benefits of CBD, including anti-anxiety, immune system regulation, pain relief, sleep, and inflammation reduction.
They also discuss what to expect when starting CBD. With different Cannabinoids in all their products, Rylee goes into the difference between THC/CBD/CBG/CBN, and why each one can be beneficial.
Robin then shares information on CBD dosage for pets while referencing different studies, and explaining the benefits seen in the each study.
Rylee then dives into the carrier oil for the True Natural Oils & Natural Pet Oil Products: MCT oil. Rylee explains why Medium Chain triglycerides are beneficial for the bioavailability of CBD & for managing energy.
Safety & Dosing is then spoken about by both Robin and Rylee in terms of the best way to take CBD, pharmaceutical drug interactions, how CBD is metabolized in the body, toxicity, and other safety concerns.
At the end, Clint speaks on testing and the quality of our products. Watch our Part 2 for Question & Answers from our team-members!
Please enjoy the following summary of the questions discussed in our Live!
Question #1: How do you start taking? Strength? Dose?
In the most simplistic terms, our Formulas are designed with a concentration to that can be begun dosing at ¼ of a dropper, and then increasing every 3 days or so until “The Sweet Spot” is reached. “The Sweet Spot” signifies the spot at which you do not notice an increase in benefits from taking a higher dosage. At that point, you reduce dosage to when you stopped seeing benefits.
We recommend starting at night, and then trying to incorporate into both Day + Night depending on desired results.
A low dosage of CBD is typically between 5-20mg per day. This may be suitable for individuals who are just starting with CBD or have a low body weight, or less symptoms to treat.
A high dosage of CBD can range from 50-150mg per day or more for Chronic Conditions.
Question #2: How long until I feel the effects of taking CBD oil? How will I know if my me or my pet is benefitting from CBD?
The time it takes for CBD oil to take effect can vary depending on several factors, such as the method of consumption, the dosage, and the individual’s metabolism. Generally, when CBD oil is ingested orally, it can take anywhere from 30 minutes to two hours to feel the effects.
CBD works with your endocannabinoid system in an interesting way; the more you consume it, the more receptive your body becomes to it. It might take some people a couple of months of continuous CBD consumption in order to fully experience the benefits of the compound. For others, they may experience effects right away. You may have different experiences with CBD from your peers because each body’s biological makeup & balance within homeostasis is different.
Also to note: CBD does NOT make you high and you will probably not feel any immediate effects when taking it. Rather, you may gradually notice the absence of some of your ailments.
Sublingual consumption (placing the oil under the tongue) can lead to faster onset of effects as it is absorbed into the bloodstream more quickly.
Topical application of CBD oil may also take some time to show effects and can depend on the area of the body where it is applied. The back of the neck has the most receptors.
Research suggests that CBD can have a half-life of 18 to 32 hours, which means that it can take around four to five days for the compound to be eliminated from the body. However, the time it takes for CBD to build up in the bloodstream and become noticeable can depend on the individual’s body chemistry and the frequency and dosage of CBD consumption.
Some signs that your pet (or you) may be benefitting from CBD oil include:
Reduced anxiety or stress
Improved mobility and joint health
Improved appetite and digestion
Improved skin (or coat) health
Improved sleep quality
It is important to keep track of yours and your pet’s behavior and health before and after starting CBD oil to determine if it is helping.
Question #3: Can I take too much?
A 2011 review article published in the journal Current Drug Safety titled “Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent.” The article summarized the existing preclinical and clinical studies on the safety and side effects of CBD and concluded that CBD is a safe and well-tolerated compound, even at high doses up to 1,500 mg/day, in humans.
Question #4: Is it addictive?
No. In contrast to pharmaceutical antidepressants, CBD does not have addictive properties. You can start and stop using it at any time without side effects. In fact, CBD is even being tested to help treat addiction (Devries ands Schoffelmeer 2005; Mahler, Smith, and Berridge 2007, Gerdeman et al. 2003b).
Question # 5: Can I develop a tolerance to CBD?
No. In 2000, there was a study published by The Kennedy Center of Rheumatology titled, “The Nonpsychoactive Cannabis Constituent Cannabidiol is an Oral Anti-arthritic Therapeutic in Murine Collagen-induced Arthritis”. The study reports that “prolonged treatment with CBD does not induce tolerance, a phenomenon often observed by cannabinoids”. This means that in contrast to many Pharmaceuticals, you will not develop a tolerance, or a reduction in efficacy as you use Cannabinoids in the treatment of your ailments. Additionally, the study ends by summarizing, “all of this suggests that CBD may be valuable in the treatment of other chronic inflammatory diseases as well.”
Question #6: What are potential side effects that someone or someone’s pet can, or has, had?
It’s important to take note of small changes in health to see how CBD is affecting you – good and bad. As with any supplement or medication, CBD can have side effects, but they are generally mild.
For humans& pets, some potential side effects of CBD include:
Dry mouth
Dizziness
Changes in appetite or weight
Fatigue
Diarrhea
Nausea
Changes in behavior or mood
Lethargy or drowsiness
Increased thirst or hunger
Vomiting
It is important to note that the side effects of CBD are generally mild and rare, but can vary depending on the individual and the dose.
Question #7: Can you explain the difference between CBD, CBG, and CBN?
CBD, or cannabidiol, is the most abundant non-psychoactive cannabinoid found in the cannabis plant. It has gained popularity in recent years due to its potential therapeutic effects, which include reducing anxiety, inflammation, and pain. CBD works by interacting with the body’s endocannabinoid system (ECS), which is a complex signaling system that regulates various physiological processes such as mood, appetite, and immune function.
CBG, or cannabigerol, is a lesser-known cannabinoid that is found in smaller amounts in the cannabis plant. It is considered a “stem cell” or “mother” cannabinoid because it is a precursor to other cannabinoids such as THC and CBD. CBG has been studied for its potential anti-inflammatory, antibacterial, and neuroprotective effects. CBG has also been studied for its potential use in treating glaucoma, inflammatory bowel disease, and other medical conditions.
CBN, found in our PM Formula, or cannabinol, is a mildly psychoactive cannabinoid that is formed as THC breaks down over time. It is found in small amounts in fresh cannabis plants but is more abundant in aged or oxidized cannabis. CBN is known for its potential sedative effects and is being studied for its potential use in treating insomnia, pain, and other medical conditions.
Question # 8: Are the True Natural Oils products safe for children or at what age do you recommend for children?
The use of CBD in children is a controversial topic, and there is limited research on its safety and effectiveness in children. For us, we use the same logic for children as we recommend for puppies: unless there is a specific condition you are looking to treat, let the child/puppy mature and equilibrate to their environment before providing a supplement.
In some cases, CBD has been prescribed by healthcare providers for children with severe epilepsy or other medical conditions, but this is done on a case-by-case basis.
