CBD topical application is considered the latest breakthrough in managing joint pain and inflammation. Together with its highly effective pain relieving properties, it possesses systemic absorption as well.
CBD is absorbed through the skin where it binds to the body’s own CB2 receptors. Once it connects with these receptors, CBD has a pain relieving and anti- inflammatory effect on the body at the site of application.
While CBD is popping up in many topical products, it’s not the only phyto-chemical within the cannabis plant to pay attention to. There are a lot of beneficial cannabinoids within cannabis, and our body has an entire system that regulates them. All of this comes into play when you slather the plant’s broad or full spectrum extracts on your skin. For example, THC has been shown to be 20 times more anti-inflammatory than aspirin and 2 times more anti-inflammatory than hydrocortisone.
Topical CBD was also found effective in alleviating the symptoms of the following conditions: oxidative stress on dermal cells, skin conditions characterized by inflammation and keratin disorders, such as eczema or atopic dermatitis, wound healing, pain & muscle relief, itch (pruritis), Acne/Seborrhea, modulation of hair growth, skin & hair pigmentation, oral care, and other skin disorders such as antibiotic-resistant skin infections, cutaneous malignancies such as Melanoma, and Psoriatic Plaques.
In terms of Arthriits, one animal study from the European Journal of Pain reports CBD “significantly reduced” joint swelling/inflammation and pain from to arthritis when applied to skin. Additionally, CBD it is even being recommended by the Arthritis Foundation.
“Several studies suggest that CBD is non-toxic in non-transformed cells and does not induce changes on food intake, does not induce catalepsy, does not affect physiological parameters (heart rate, blood pressure and body temperature), does not affect gastrointestinal transit and does not alter psychomotor or psychological functions. Also, chronic use and high doses up to 1,500 mg/day of CBD are reportedly well tolerated in humans.”
Reference: Bergamaschi MM, Queiroz RH, Zuardi AW, Crippa JA. Safety and side effects of cannabidiol, a Cannabis sativa constituent. Curr Drug Saf. 2011 Sep 1;6(4):237-49. doi: 10.2174/157488611798280924. PMID: 22129319.
In 2000, there was a study published by The Kennedy Center of Rheumatology titled, “The Nonpsychoactive Cannabis Constituent Cannabidiol is an Cral Anti-arthritic Therapeutic in Murine Collagen-induced Arthritis”. The study ends by summarizing, “all of this suggests that CBD may be valuable in the treatment of other chronic inflammatory diseases as well.”
What’s even better, this study also reports that “prolonged treatment with CBD does not induce tolerance, a phenomenon often observed by cannabinoids”. This means that in contrast to many Pharmaceuticals, you will not develop a tolerance, or a reduction in efficacy as you use Cannabinoids in the treatment of your ailments.
Cannabis affects the body because its bioactive compounds bind to and activate tiny receptors encoded by our genes.
The brain and nervous system contain a different set of receptors (CB1) than the receptors used primarily in our immune system/inflammation (CB2).
Because CB2 activation dampens inflammatory responses, it has the potential to serve as a molecular target for diminishing inflammation linked to pathogenic disorders such as MS, ischemic/perfusion injury following an induced stroke, rheumatoid arthritis, inflammatory bowel disease and osteoporosis pain. (Centonze et. al 2007) .
Neuroinflammation is key to both autoimmune disorders (multiple sclerosis, lupus, psoriasis, etc) and Neurodegenerative diseases (Alzheimer’s, Parkinson’s, Huntington’s, etc) (Wolf Tauber, and Ullrich 2008; Pryce, Jackson and Baker 2008).
Disclaimer: not medical advice. These products are not approved by the FDA to treat, diagnose, or cure any disease.
A study has showed that a single dose of CBD, administered orally in healthy volunteers, alters the resting activity in limbic and paralimbic brain areas while decreasing subjective anxiety associated with the scanning procedure.
In healthy humans, CBD reversed the anxiogenic (anxiety-inducing) effects of Δ9-THC and reduced anxiety in a simulated public-speaking task.
CBD Oil can taste anywhere from grassy, nutty, or even chemically depending on quality and extraction method. True Natural Oils triumphs using pure full-spectrum CBD oil, USDA certified organic MCT coconut oil, and added organic flavors to complement the existing natural terpene profile.
True Natural Oils was able to retain the delicate terpenes in the extraction process, giving True Wellness the aromatic smell of mint, with refreshing hints of citrus. True Bliss carries hints of berry with added relaxing botanicals. True Fusion is our champion formula focusing on anti-inflammation and deep stress relief accented by hints of natural cinnamon.
We have received much positive feedback about the flavors of our products with reviews ending in comments such as, “Oh, i forgot to mention the flavors are fantastic,” or “And, by the way, the flavors infused in all the products are incredible!” (Reviews submitted & published on website)
Our CBD oils can be delicious to take on their own and fun to use when cooking with CBD. The fun part about our flavored CBD oil is it can easily be added to beverages such as tea, coffee, mocktails, or cocktails. You can also incorporate them into other fun things like salad dressings and sauces and smoothies
The current data support the notion that the anti-inflammatory function of CBD may reduce cytokine storm and mitigate the effects of exaggerated inflammation the authors explain. Further adding that, considering all potential regulatory effects of CBD as well as the vast distribution of endocannabinoid system in the body, it is plausible that CBD may be used as a therapeutic candidate in the treatment of various inflammatory conditions including COVID-19 and other virus-induced ARDS.
With this being an early study, more research needs to be performed, particularly on human subjects with COVID-19 related ARDS to validate and expand this therapeutic strategy. This evidence on the additional health benefits of CBD provides hope in the uncharted waters of not only COVID-19 but other illnesses as well, hopefully ending the stigma of this enlightening cannabis plant.
As researchers and doctors rush to understand the novel coronavirus, sometimes new evidence contradicts old claims. Cannabis represents a main topic where scientists have spun 180 degrees in discussing how the plant interacts with COVID-19. Public health officials announced back in March that marijuana smokers and vapers were more at risk to contract and spread the coronavirus.
Lung health experts still don’t recommend inhaling any combustible material like tobacco or marijuana, due to the inflammation caused in your airways. However, cannabis has emerged as an unlikely candidate in preventing and treating COVID-19 symptoms.
Following a study conducted at the University of Lethbridge in Alberta, Canada, researchers believe that strong cannabis strains could prove valuable in preventing or treating coronavirus infections.
Their study led them to hypothesize that those extracts high in CBD could be leveraged to combat Covid-19 infections by modulating levels of ACE2 (angiotensin-converting enzyme II) in certain “gateway” tissues.
These include lung tissue, oral/nasal mucosa, gastrointestinal tract, kidney, and testes. The researchers believe that modulating ACE2 levels in these areas with CBD could help to decrease people’s susceptibility to Covid-19. As the coronavirus can only enter a human host with a receptor, i.e. ACE2, targeting these could reduce the risk of infection significantly.
Its goal is to determine whether CBD can increase the effectiveness of corticosteroids (a key treatment for autoimmune illnesses) or allow for steroid dosages to reduce while enhancing their effect.
The research conducted by Stero Therapeutics and the University of Lethbridge’s team could open the doors to unexpected new ways to prevent, and treat, coronavirus. However, further studies will be required to verify the research and facilitate the creation of CBD-centric solutions suitable for COVID-19 patients.
Whatever the outcome, the need for an effective treatment is urgent.
As COVID-19 cases continue to rise, researchers have started to look for solutions in an unlikely place – the cannabis plant. Cannabis’ active compounds have a number of properties that make it appealing as a potential adjunct treatment for infections from the novel coronavirus, and recently scientists have begun looking at its potential for reducing susceptibility to the disease, and even discussed whether it could be used as an antiviral medication.
This month, researchers from the University of Nebraska and the Texas Biomedical Research Institute are recommending more research into how cannabis-derived CBD might help treat dangerous lung inflammation from the novel coronavirus. The authors detailed the evidence for how cannabis’ anti-inflammatory powers may help in a peer reviewed article in this month’s issue of Brain, Behavior, and Immunity.
In the article, researchers explain that “recent reports have suggested that acute infection is associated with a cytokine superstorm, which contributes to the symptoms of fever, cough, muscle pain.” These extreme instances of inflammation can lead to severe pneumonia which clog up the lungs, make breathing difficult or impossible. So, one of the important strategies that scientists are studying in the fight against COVID-19 is reducing inflammation.