Yes. For optimal drug delivery, the buccal (cheek) and sublingual (under the tongue) dosage forms must remain in contact with oral mucosa for a time of 60 to 90 seconds.
A common problem associated with trans mucosal administration via the buccal(cheek) route, is swallowing the dose due to the continuous secretion of saliva in the oral cavity. More specifically, the dosage form must not be washed away by saliva into the gastrointestinal tract.
The following is how we take our tinctures:.
1.) 3000mg/30ml TRUE FUSION 100mg/ml. – dose 0.5 ml (1/2 dropperful) twice daily = 100mg/day hold under tongue for 1minute to optimize absorption.
2.) 1500mg/30ml product TRUE BLISS 50mg/ml. – dose 0.5ml – 1.0 ml twice to three times daily. 25mg to 50mg , 2-3 times a day. 0.5ml=(1/2 dropperful) hold under tongue for 1minute to optimize absorption.
3.) 750mg /30ml product TRUE WELLNESS 25mg/ml. – dose 1 ml up to 2 ml in the evening for restful sleep. 0.5 ml = (1/2 dropperful) hold under tongue for 1minute to optimize absorption.
“Several studies suggest that CBD is non-toxic in non-transformed cells and does not induce changes on food intake, does not induce catalepsy, does not affect physiological parameters (heart rate, blood pressure and body temperature), does not affect gastrointestinal transit and does not alter psychomotor or psychological functions. Also, chronic use and high doses up to 1,500 mg/day of CBD are reportedly well tolerated in humans.”
Reference: Bergamaschi MM, Queiroz RH, Zuardi AW, Crippa JA. Safety and side effects of cannabidiol, a Cannabis sativa constituent. Curr Drug Saf. 2011 Sep 1;6(4):237-49. doi: 10.2174/157488611798280924. PMID: 22129319.
In 2000, there was a study published by The Kennedy Center of Rheumatology titled, “The Nonpsychoactive Cannabis Constituent Cannabidiol is an Cral Anti-arthritic Therapeutic in Murine Collagen-induced Arthritis”. The study ends by summarizing, “all of this suggests that CBD may be valuable in the treatment of other chronic inflammatory diseases as well.”
What’s even better, this study also reports that “prolonged treatment with CBD does not induce tolerance, a phenomenon often observed by cannabinoids”. This means that in contrast to many Pharmaceuticals, you will not develop a tolerance, or a reduction in efficacy as you use Cannabinoids in the treatment of your ailments.
A study has showed that a single dose of CBD, administered orally in healthy volunteers, alters the resting activity in limbic and paralimbic brain areas while decreasing subjective anxiety associated with the scanning procedure.
In healthy humans, CBD reversed the anxiogenic (anxiety-inducing) effects of Δ9-THC and reduced anxiety in a simulated public-speaking task.
CBD Oil can taste anywhere from grassy, nutty, or even chemically depending on quality and extraction method. True Natural Oils triumphs using pure full-spectrum CBD oil, USDA certified organic MCT coconut oil, and added organic flavors to complement the existing natural terpene profile.
True Natural Oils was able to retain the delicate terpenes in the extraction process, giving True Wellness the aromatic smell of mint, with refreshing hints of citrus. True Bliss carries hints of berry with added relaxing botanicals. True Fusion is our champion formula focusing on anti-inflammation and deep stress relief accented by hints of natural cinnamon.
We have received much positive feedback about the flavors of our products with reviews ending in comments such as, “Oh, i forgot to mention the flavors are fantastic,” or “And, by the way, the flavors infused in all the products are incredible!” (Reviews submitted & published on website)
Our CBD oils can be delicious to take on their own and fun to use when cooking with CBD. The fun part about our flavored CBD oil is it can easily be added to beverages such as tea, coffee, mocktails, or cocktails. You can also incorporate them into other fun things like salad dressings and sauces and smoothies