Tag: pain

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CBD: The Solution for Fall Seasonal Challenges & Wellness

CBD (cannabidiol), the main active ingredient in our products has gained popularity for its potential therapeutic benefits. Our CBD products have been to seen to help with several issues that can be more prevalent during the fall season:

  1. Seasonal Affective Disorder (SAD): SAD is a type of depression that typically occurs in the fall and winter months when there is less natural sunlight. Some people use CBD to help manage the symptoms of SAD, such as low mood and energy levels.
  2. Anxiety and Stress: The fall season can bring about increased stress and anxiety for some people, particularly as holidays approach. CBD is often used as a natural remedy to promote relaxation and reduce anxiety.
  3. Pain and Inflammation: Fall can be associated with more outdoor activities, and some individuals may experience joint pain or inflammation due to changing weather conditions. CBD may have pain-relieving and anti-inflammatory properties.
  4. Sleep Issues: The transition to cooler and darker days in the fall can disrupt sleep patterns. CBD has been used by some individuals to help improve sleep quality and address insomnia.
  5. Immune Support: As the flu season approaches, some people turn to CBD for its potential anti-inflammatory and immune-supporting properties.

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Disclaimer: Not Medical Advice.

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Exploring the Benefits and Potential of Cannabigerol: Featured in All Our Products!

CBG is found in all of our products!

CBG, or cannabigerol, is a lesser-known cannabinoid that is found in smaller amounts in the cannabis plant. It is considered a “stem cell” or “mother” cannabinoid because it is a precursor to other cannabinoids such as THC and CBD. CBG has been studied for its potential anti-inflammatory, antibacterial, and neuroprotective effects. CBG has also been studied for its potential use in treating glaucoma, inflammatory bowel disease, and other medical conditions:

  1. Glaucoma: CBG has been shown to have potential neuroprotective effects and may be useful in treating glaucoma, a condition that damages the optic nerve and can lead to vision loss. Merrick J, et al. (2016). Identification of psychoactive degradants of cannabigerol in artificial gastric and physiological fluid. DOI: 10.1007/s00216-015-8688-4
  2. Inflammatory bowel disease (IBD): CBG has been shown to have potential anti-inflammatory effects and may be useful in treating IBD, a group of inflammatory conditions that affect the digestive tract. Borrelli F, et al. (2013). Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease. DOI: 10.1038/srep04216
  3. Cancer: CBG has been shown to have potential anti-cancer effects in some preclinical studies, and may be useful in treating certain types of cancer.
  4. Huntington’s disease: CBG has been shown to have potential neuroprotective effects and may be useful in treating Huntington’s disease, a rare genetic disorder that causes progressive degeneration of brain cells. Valdeolivas S, et al. (2015). Neuroprotective properties of cannabigerol in Huntington’s disease: Studies in R6/2 mice and 3-nitropropionate-lesioned mice. DOI: 10.1016/j.ejphar.2015.07.011
  5. Bladder dysfunction: CBG has been shown to have potential therapeutic effects on bladder dysfunction, including overactive bladder and urinary incontinence.
  6. Antibiotic-resistant infections: CBG has been shown to have potential antibacterial effects and may be useful in treating antibiotic-resistant infections caused by bacteria such as MRSA. Appendino G, et al. (2008). Antibacterial cannabinoids from Cannabis sativa: A structure-activity study. DOI: 10.1021/np8002673
  7. Psoriasis: CBG has been shown to have potential anti-inflammatory effects and may be useful in treating psoriasis, a chronic inflammatory skin condition. Wilkinson JD, et al. (2007). Cannabinoids inhibit human keratinocyte proliferation through a non-CB1/CB2 mechanism and have a potential therapeutic value in the treatment of psoriasis. DOI: 10.1111/j.1476-5381.2007.00379.
  8. Pain: CBG has been shown to have potential analgesic (pain-relieving) effects and may be useful in treating various types of pain, including neuropathic pain. Russo EB. (2008). Cannabinoids in the management of difficult to treat pain. DOI: 10.1089/can.2008.0012
  9. Anxiety and depression: CBG has been shown to have potential anxiolytic (anti-anxiety) and antidepressant effects in some preclinical studies. Galaj E, et al. (2020). The role of cannabigerol in reducing anxiety and depression in preclinical models. DOI: 10.3390/ijms21072350
  10. Multiple sclerosis (MS): CBG has been shown to have potential anti-inflammatory effects and may be useful in treating MS, a chronic inflammatory disease that affects the central nervous system. ElSohly MA, et al. (2014). Stability indicating HPLC-UV determination of cannabidiol (CBD) and delta9-tetrahydrocannabinol (THC) in bulk drug and pharmaceutical dosage form. DOI: 10.1016/j.jpba.2013.12.014
  11. Neurodegenerative disorders: CBG has been shown to have potential neuroprotective effects and may be useful in treating neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis (ALS). Valdeolivas S, et al. (2012). Cannabigerol attenuates the progression of abeta in vitro and in vivo. DOI: 10.3233/JAD-2012-120675
  12. Acne: CBG has been shown to have potential anti-inflammatory effects and may be useful in treating acne, a common skin condition caused by inflammation. Oláh A, et al. (2016). Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes. DOI: 10.1111/exd.13042
  13. Bone growth: CBG has been shown to have potential osteogenic effects, meaning it may promote bone growth and could be useful in treating conditions such as osteoporosis. Kogan NM, et al. (2015). Cannabidiol, a major non-psychotropic cannabis constituent enhances fracture healing and stimulates lysyl hydroxylase activity in osteoblasts. DOI: 10.1016/j.bone.2015.07.022
  14. Insomnia: CBG has been shown to have potential sedative effects and may be useful in treating insomnia, a sleep disorder that makes it difficult to fall asleep or stay asleep.
  15. Appetite stimulation: CBG has been shown to have potential appetite-stimulating effects and may be useful in treating conditions that cause decreased appetite or weight loss. Farrimond JA, et al. (2012). Cannabinol and cannabidiol exert opposing effects on rat feeding patterns. DOI: 10.1007/s00213-012-2697-x
  16. Cardiovascular disease: CBG has been shown to have potential cardioprotective effects and may be useful in treating cardiovascular diseases such as hypertension and atherosclerosis.
  17. Diabetes: CBG has been shown to have potential antidiabetic effects and may be useful in treating diabetes, a metabolic disorder characterized by high blood sugar levels.
  18. Cardiovascular disease: Bátkai S, et al. (2005). Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension. DOI: 10.1161/01.HYP.0000154767.10345.9c
  19. Parkinson’s disease: In a preclinical study published in the journal Movement Disorders in 2013, researchers found that CBG had potential symptom-relieving and neuroprotective effects in animal models of Parkinson’s disease. Specifically, CBG was found to have antioxidant and anti-inflammatory properties, which may help to protect neurons in the brain from damage and degeneration. García C, et al. (2011). Symptom-relieving and neuroprotective effects of the phytocannabinoid Δ9-THCV in animal models of Parkinson’s disease. DOI: 10.1002/mds.25928
  20. Alcohol addiction: In a preclinical study published in the journal Alcohol and Alcoholism in 2018, researchers found that CBG reduced alcohol intake in rodents. The study also showed that CBG reduced the expression of a protein called GPR55 in the placenta, which is associated with the negative effects of prenatal alcohol exposure. However, more research is needed to determine the potential therapeutic effects of CBG on alcohol addiction in humans. Viudez-Martínez A, et al. (2018). Cannabigerol reduces alcohol intake and placental GPR55 receptors. DOI: 10.1111/acer.13810
  21. Antibacterial activity: Appendino G, et al. (2008). Antibacterial cannabinoids from Cannabis sativa: A structure-activity study. DOI: 10.1021/np8002673

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FAQ: What is the Recommended Dosage of CBD?

The recommended dosage of CBD can vary depending on a variety of factors, including body weight, individual tolerance, the condition being treated, and the form of CBD being used (such as oil, capsules, or topicals). It’s always best to consult with a healthcare professional before starting to use CBD, as they can provide personalized recommendations based on your specific needs.

That being said, some general guidelines for dosing CBD have been suggested by experts. A common starting dose is around 5-10mg of CBD, taken once or twice daily. From there, the dosage can be gradually increased over time as needed, up to a maximum of around 1500mg per day. It’s important to start with a low dose and gradually increase it to assess how your body responds to CBD and to minimize the risk of any potential side effects.

CBD (cannabidiol) is generally considered safe, with few reported side effects. According to the World Health Organization (WHO), CBD is well-tolerated by most people and is not associated with abuse potential or dependence. However, as with any supplement or medication, CBD can interact with other medications, so it’s important to talk to a healthcare provider before using CBD if you are taking any prescription medications or have any underlying medical conditions.

Some potential side effects of CBD may include drowsiness, dry mouth, lightheadedness, and changes in appetite or weight. These side effects are generally mild and temporary, and may be less likely to occur at lower doses.

It’s important to note that the safety of CBD products can vary depending on factors such as the quality and purity of the product, as well as how it is manufactured and used. It’s always best to purchase CBD products from reputable sources, and to follow the recommended dosages and usage guidelines.

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FAQ: How Long Does It Take For CBD To Take Effect?

The time it takes for CBD to take effect can vary depending on a variety of factors, including the form of CBD being used (such as oil, capsules, or topicals), the dose, and the individual’s metabolism and body chemistry.

When using CBD oil or capsules, it can take anywhere from 30 minutes to an hour or more for the effects to be felt. This is because the CBD must first be absorbed into the bloodstream through the digestive system. However, if the CBD is taken sublingually (under the tongue), the effects may be felt more quickly, as the CBD can be absorbed into the bloodstream more rapidly through the blood vessels under the tongue.

When using a topical form of CBD, such as a cream or lotion, the effects are typically localized to the area where it is applied and may be felt more quickly than when using oral forms of CBD.

It’s important to note that the effects of CBD can also be cumulative over time, meaning that regular use may result in more consistent and noticeable effects. Additionally, individual experiences with CBD can vary, so it’s important to monitor your own response and adjust the dosage as needed.

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FAQ: How Can CBD help in Aging?

As we age, we can experience slower metabolism, increased likelihood of polypharmacy, cognitive decline and chronic physical/mental health problems.

CBD has no intoxicating effects or abuse liability, and because of its widespread activity in the Endocannabinoid System in the body, it has been proposed to be beneficial therapeutically for a variety of health conditions in people of all ages.

Generally, older adults suffer from more chronic medical and mental health conditions (eg, chronic pain, insomnia, and mood and cognitive disorders) than younger adults.  Experts say CBD use will continue to gain momentum in the health and wellness world, with some scientific studies confirming it may ease symptoms of ailments like chronic pain, inflammation, and anxiety.

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FAQ: What are Terpenes & how can they help our Health?

Let’s Talk Terpenes! The many pleasant terpenes not only impart flavor and aroma, but also offer healing properties. These terpenes are widely represented elsewhere in nature in aromatic foods, spices, and tree resins, including broccoli, citrus fruits, mangoes, beer, basil, rosemary, cinnamon, and oregano. Here’s a quick overview:

🌿 Alpha-pinene terpenes are said to help enhance focus and memory. They are also thought to have bronchodilator, anti-inflammatory, and antimicrobial properties.

🌿 Linalool (lavender) is a sedative, anti-epileptic, and analgesic that also can help reduce anxiety.

🌿 Myrcene (mango) is analgesic, muscle-relaxing, and antibiotic.

🌿 Beta-caryophyllene (clove), known as the “happy” terpene, reduces anxiety, lifts spirits, and acts as an antioxidant and antimicrobial.

🌿 Limonene (lemon peel) improves mood, reduces anxiety and depression, and boosts immunity.

All True Natural Oils products contain large, quantifiable amounts of cannabinoids. This can be verified by looking at the independent lab test results posted on our website. It is very important to check lab reports before purchasing CBD products. We provide ours by scanning the QR code on the side of your box!

Terpenes extracted from cannabis offer a wide range of benefits when combined with CBD. In fact, when terpenes work together with CBD, they create a stronger effect. They deliver a richer experience by producing this synergistic phenomenon known as the Entourage Effect. Think of it as a treat to yourself!

To fully grasp this concept, think of human interactions in the business world. Some people have particular gifts or special abilities that allow them to excel in a subject or a field. Sometimes, these people meet other individuals who have a different set of skills. When alliances are formed between these two groups of people, and abilities are combined, progress can be made that were otherwise improbable.

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FAQ: How can CBD help my Diabetes?

Diabetic Neuropathies (DPNs) is the most common complication associated with diabetes and is a leading cause of disability due to foot ulcerations, fall risks and can lead to infection and limb amputation. 

CBD play roles in modulating neurotransmission and immune function.

When a nerve is injured or damaged, nociceptive (pain receptor) pathways and the immune system are affected, and the dysregulation of these neuroimmune processes has been associated with pain.

Topical CBD was found to help with both joint neuropathy and osteoarthritis by serving as a protectant to the nerves and reducing joint inflammation.

One of the reasons why using CBD oil topically is preferred for arthritis pain or neuropathy is because when applied topically, Cannabidiol has a direct and targeted impact on the affected body joints, muscles and nerves. In other words, topical CBD offers localized relief.

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FAQ: What does the World Health Organization (WHO) say about CBD?

The following is page 18/27 of The World Health Organization’s report on CBD’s potential benefits:

https://www.who.int/medicines/access/controlled-substances/5.2_CBD.pdf

In terms of safety, the WHO reports:

“In humans, CBD exhibits no effects indicative of any abuse or dependence potential.”

“To date, there is no evidence of recreational use of CBD or any public health related problems associated with the use of pure CBD.”

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FAQ: Is CBD Effective Topically?

CBD topical application is considered the latest breakthrough in managing joint pain and inflammation. Together with its highly effective pain relieving properties, it possesses systemic absorption as well. ⁣

⁣CBD is absorbed through the skin where it binds to the body’s own CB2 receptors. Once it connects with these receptors, CBD has a pain relieving and anti- inflammatory effect on the body at the site of application.⁣

While CBD is popping up in many topical products, it’s not the only phyto-chemical within the cannabis plant to pay attention to. There are a lot of beneficial cannabinoids within cannabis, and our body has an entire system that regulates them. All of this comes into play when you slather the plant’s broad or full spectrum extracts on your skin.⁣ For example, THC has been shown to be 20 times more anti-inflammatory than aspirin and 2 times more anti-inflammatory than hydrocortisone.

The spectrum of cannabinoids work in concert more efficiently and effectively on these receptors than one on its own—hence it’s good to look for the whole plant’s extract infused with the plant’s helpful terpenes such as our True Natural Oils lotion or Golden Bee Hemp Pain Salve available here.

Topical CBD was also found effective in alleviating the symptoms of the following conditions: oxidative stress on dermal cells, skin conditions characterized by inflammation and keratin disorders, such as eczema or atopic dermatitis, wound healing, pain & muscle relief, itch (pruritis), Acne/Seborrhea, modulation of hair growth, skin & hair pigmentation, oral care, and other skin disorders such as antibiotic-resistant skin infections, cutaneous malignancies such as Melanoma, and Psoriatic Plaques.

In terms of Arthriits, one animal study from the European Journal of Pain reports CBD “significantly reduced” joint swelling/inflammation and pain from to arthritis when applied to skin. Additionally, CBD it is even being recommended by the Arthritis Foundation.

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FAQ: Can I take CBD if I am on Opioids?

“Since opioids are the only therapy for severe pain, analgesic ability of cannabinoids may provide a much-needed alternative to opioids. Moreover, cannabinoids act synergistically with opioids and act as opioid sparing agents, allowing lower doses and fewer side effects from chronic opioid therapy. Thus, rational use of cannabis based medications deserves serious consideration to alleviate the suffering of patients due to severe pain.”⁣.

Reference: Elikkottil, Jaseena et al. “The analgesic potential of cannabinoids.” Journal of opioid management vol. 5,6 (2009): 341-57.⁣

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