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What Is the Entourage Effect and why is it a “Treat”?

Terpenes extracted from cannabis offer a wide range of benefits when combined with CBD. In fact, when terpenes work together with CBD, they create a stronger effect. 

They deliver a richer experience by producing this synergistic phenomenon known as the Entourage Effect.  Think of it as a treat to yourself!

To fully grasp this concept, think of human interactions in the business world. Some people have particular gifts or special abilities that allow them to excel in a subject or a field. Sometimes, these people meet other individuals who have a different set of skills. When alliances are formed between these two groups of people, and abilities are combined, progress can be made that were otherwise improbable.

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ORAL DOSAGE VIA BUCCAL MUCOSA

A common problem associated with trans mucosal administration via the buccal route, is swallowing the dose due to the continuous secretion of saliva in the oral cavity. This contributes to observed pharmacokinetics variability of oral cannabinoid sprays and aerosols. For optimal drug delivery the buccal and sublingual dosage forms must remain in contact with oral mucosa for a time of 60 to 90 seconds.

More specifically, the dosage form must not be washed away by saliva into the gastrointestinal tract.

1.) 3000mg/30ml TRUE FUSION 100mg/ml. – dose 0.5 ml (1/2 dropperful) twice daily = 100mg/day hold under tongue for 1minute to optimize absorption

2.) 1500mg/30ml product TRUE BLISS 50mg/ml. – dose 0.5ml – 1.0 ml twice to three times daily. 25mg to 50mg , 2-3 times a day. 0.5ml=(1/2 dropperful) hold under tongue for 1minute to optimize absorption

3.) 750mg /30ml product TRUE WELLNESS 25mg/ml. – dose 1 ml up to 2 ml in the evening for restful sleep. 0.5 ml = (1/2 dropperful) hold under tongue for 1minute to optimize absorption

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Robin’s Write up

Hope everyone has  had a wonderful past month and experienced wellness and good health.

I have a terrific testimony to share with you. A story and experience a lady shared with me while we were sitting in the airport awaiting our next flight.  The motive of the topic was exclaiming that the flu was still raging in full force. And what worse than to be sitting in an airplane full of people. She had mentioned she was just coming back from a cross-country flight from the East Coast. While there, she was taking care of her mother who was in a nursing home. She explained she spent quite a bit of time in the nursing home.

The problem was the patients were All quarantined from an upper respiratory illness that was running rampant through the nursing home. Also, while there, she was battling the frigid temperatures and snowy conditions. She then told me that she was feeling as though she was coming down with The beginnings of an upper respiratory bronchial type of illness. She then shared with me that she had been taking CBD oil and all throughout this winter season it has kept her well. She went on to say that she was doubling her dose of CBD oil while she was feeling sick and it seemed to thwart the development of the bronchitis. 

I, of course, interjected my thoughts on the topic and told her she was absolutely correct! The immunological benefits of CBD oil to support the immune system through supporting the cells that fight infection are extraordinary. I told her that daily administration of CBD oil truly would keep away most illnesses. As for her story to me, the lady that I briefly encountered in the airport, just goes to prove that this incredible oil is maintaining wellness across the nation. It was wonderful to talk to her that day about this particular topic!

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CBD Oil, Skin Care, Inflammation and Pain relief

Most cannabinoid skin-care products are designed to help achy spots or surface issues such as eczema. But those applications are just the tip of the iceberg as CBD Cannabis oil seems to give you an extra layer of protection, helping your skin fight against everyday wear-and-tear and some nasty diseases.

Did you know that cannabis oil contains all 21 known amino acids? Plus it’s rich in essential fatty acids such as Omega-3 and Omega-6 which are vital for our internal body and skin. These acids help combat daily problems that our skin is the first to take on, whether it be from inclement weather, sun exposure, dry climates, UV or other daily factors. Problems that can lead to a variety of medical issues such as eczema, psoriasis and even skin cancer.

But wait, that’s not all. The major component in the oil known as CBD, is an antioxidant that is even more powerful than Vitamin C,E,A or omega 3 fatty acids.

A recent study in the British Journal of Pharmacology found that CBD and cannabigerol (CBG), can control cell proliferation and differentiation, meaning they can be used as treatments for skin diseases like cancer or allergies.

CBD is also known to be anti-inflammatory, analgesic, antispasmodic, cell-regenerative, and anti–cell proliferative for bad cells. This means that CBD is a potential therapy for a range of medical conditions.

CBD topical application is considered the latest breakthrough in managing joint pain and inflammation. Together with its highly effective pain relieving properties, it possesses systemic absorption as well. CBD is absorbed through the skin where it binds to the body’s own CB2 receptors. Once it connects with these receptors, CBD has a pain relieving an anti- inflammatory effect on the body at the site of application.

While CBD is the compound popping up in beauty products, it’s not the only one within the cannabis plant to be aware of. 

Real talk: There are a lot of chemicals within cannabis, and our body has an entire system that regulates them. All of this comes into play when you slather the plant’s extracts on your skin.

If you just have one cannabinoid, such as CBD, you’re missing out on the over 100 additional cannabinoids that work together to produce the entourage effect.  We really believe in the whole plant, full-spectrum extract or oil, with added terpenes, as the active ingredient in skin-care products.  In other words, you want the whole system working together. 

Your body’s endocannabinoid system has receptors, the full spectrum of cannabinoids work in concert more efficiently and effectively than one on its own—hence it’s good to look for the whole plant’s extract infused with the helpful terpenes.

Topical CBD was also found effective in alleviating the symptoms of the following conditions: seizures, spasticity, weakness, pain, anxiety, insomnia, trigeminal neuralgia, autism, ADD, peripheral neuropathy and fibromyalgia.

The best proven site for application is at the back of the neck. This area is rich with Hundreds of thousands of free nerve endings below the skin surface. No other location has such a magnitude of afferent neural input accessible through skin nerve endings. This source of application of CBD is beneficial in treating symptoms of a number of neuropathic and psychiatric conditions. Topical CBD therapy is overall well tolerated. For example, studies performed by scientific researchers, through the route of topical back of the neck CBD application, found complete seizure freedom achieved in a number of patients with previous intractable epilepsy on multiple drug regimen.

Dosing frequency of topical application range from once daily to three times daily depending on severity of condition. The duration of treatment with topical CBD range from several days to as needed.