A common problem associated with trans mucosal administration via the buccal route, is swallowing the dose due to the continuous secretion of saliva in the oral cavity. This contributes to observed pharmacokinetics variability of oral cannabinoid sprays and aerosols. For optimal drug delivery the buccal and sublingual dosage forms must remain in contact with oral mucosa for a time of 60 to 90 seconds.
More specifically, the dosage form must not be washed away by saliva into the gastrointestinal tract.
1.) 3000mg/30ml TRUE FUSION 100mg/ml. – dose 0.5 ml (1/2 dropperful) twice daily = 100mg/day hold under tongue for 1minute to optimize absorption
2.) 1500mg/30ml product TRUE BLISS 50mg/ml. – dose 0.5ml – 1.0 ml twice to three times daily. 25mg to 50mg , 2-3 times a day. 0.5ml=(1/2 dropperful) hold under tongue for 1minute to optimize absorption
3.) 750mg /30ml product TRUE WELLNESS 25mg/ml. – dose 1 ml up to 2 ml in the evening for restful sleep. 0.5 ml = (1/2 dropperful) hold under tongue for 1minute to optimize absorption