Tag: CBD

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One preliminary study suggests CBD may help to fight Covid-19

Following a study conducted at the University of Lethbridge in Alberta, Canada, researchers believe that strong cannabis strains could prove valuable in preventing or treating coronavirus infections.

Their study led them to hypothesize that those extracts high in CBD could be leveraged to combat Covid-19 infections by modulating levels of ACE2 (angiotensin-converting enzyme II) in certain “gateway” tissues.

These include lung tissue, oral/nasal mucosa, gastrointestinal tract, kidney, and testes. The researchers believe that modulating ACE2 levels in these areas with CBD could help to decrease people’s susceptibility to Covid-19. As the coronavirus can only enter a human host with a receptor, i.e. ACE2, targeting these could reduce the risk of infection significantly.

Its goal is to determine whether CBD can increase the effectiveness of corticosteroids (a key treatment for autoimmune illnesses) or allow for steroid dosages to reduce while enhancing their effect.

The research conducted by Stero Therapeutics and the University of Lethbridge’s team could open the doors to unexpected new ways to prevent, and treat, coronavirus. However, further studies will be required to verify the research and facilitate the creation of CBD-centric solutions suitable for COVID-19 patients.

Whatever the outcome, the need for an effective treatment is urgent. 

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Cannabis May Reduce Deadly COVID-19 Lung Inflammation: Researchers Explain Why

As COVID-19 cases continue to rise, researchers have started to look for solutions in an unlikely place – the cannabis plant. Cannabis’ active compounds have a number of properties that make it appealing as a potential adjunct treatment for infections from the novel coronavirus, and recently scientists have begun looking at its potential for reducing susceptibility to the disease, and even discussed whether it could be used as an antiviral medication. 

This month, researchers from the University of Nebraska and the Texas Biomedical Research Institute are recommending more research into how cannabis-derived CBD might help treat dangerous lung inflammation from the novel coronavirus. The authors detailed the evidence for how cannabis’ anti-inflammatory powers may help in a peer reviewed article in this month’s issue of Brain, Behavior, and Immunity.

In the article, researchers explain that “recent reports have suggested that acute infection is associated with a cytokine superstorm, which contributes to the symptoms of fever, cough, muscle pain.” These extreme instances of inflammation can lead to severe pneumonia which clog up the lungs, make breathing difficult or impossible. So, one of the important strategies  that scientists are studying in the fight against COVID-19 is reducing inflammation. 

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CBD For Coronavirus? New Study Adds Evidence For Cannabis As Covid-19 Treatment

As we continue to see outbreaks of the novel coronavirus surging, many are waiting and hoping for treatments to be developed that might treat, cure or prevent the potentially deadly disease. In a surprising turn of events, cannabis is on the list of potential treatments. 

While researchers are exploring many different possibilities in combating COVID-19, some researchers are looking into whether cannabis or cannabis derived CBD might offer benefits for those suffering from severe forms of this infection. Interestingly, there have been several different ways researchers have suggested CBD might help, including its ability to reduce ACE2 expression and pro-inflammatory cytokine production to fight lung inflammation, and it’s potential as an antiviral. But few studies have tested these theories with actual experimentation.  

Now new evidence is adding support to the theory that cannabis derived CBD may help those suffering from the severe lung inflammation that occurs in more serious cases of COVID-19. The study from researchers at Augusta University in Georgia suggests  that CBD may positively impact ARDS or acute respiratory distress syndrome – a dangerous symptom in COVID-19 caused by an overactive inflammatory response. This is sometimes referred to as a ‘cytokine storm’. The authors of the study explain that “currently, other than supportive measures, there is no definitive cure for ARDS, illustrating the urgent need for creative and effective therapeutic modalities to treat this complex condition.”

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New Research Suggests Terpenes And CBD Work 2X’s Better For Covid-19 Inflammation Than Corticosteroid

In the fight against Covid-19, cytokine storms are one of the most deadly factors that doctors are battling. This symptom in severe cases of the novel coronavirus can lead to excessive inflammation, swelling, pain, and loss of organ function. It can even cause the immune system to ramp up so much that it starts killing the body’s own cells – instead of just fighting the infection. In serious cases, this can lead to death, as we’ve seen in many cases of severe Covid-19. 

In the last few months,  researchers have been looking at whether cannabis, or it’s many chemical compounds, might help to fight this deadly effect by bringing down inflammation. Recently, we’ve seen positive results from studies suggesting that CBD, a compound in cannabis, may help fight these cytokine storms. 

Now early results from an ongoing Israeli study are adding to the chorus of researchers suggesting that cannabis’ ingredients could be a game changing treatment in the fight against Covid-19. But this study says that terpenes, compounds that provide the aroma and flavor in cannabis and many other plants, may lead to even better results than CBD alone, and might outperform conventional treatments like corticosteroids. Reports from the study show that a combination of CBD with terpenes was 3 times more effective at inhibiting cytokine activity than dexamethasone, a corticosteroid which a recent study found to be an effective treatment for Covid-19 cytokine storms. 

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Feeling Stress and Anxiety?

Feeling stress and anxiety in small doses is normal and natural, but too much of it at once can negatively affect you over time. It’s in your own best interest to manage your feelings and emotions healthily so you can maintain control over your thoughts and actions. For example, a natural remedy for reducing stress and anxiety is to purchase CBD from True Natural Oils and use it regularly to help you feel better fast.

You’ll find life to be more rewarding and not so chaotic and frustrating. Let this be a time for you to focus on your own personal growth and discovering new habits that help you to live a more fulfilling existence. You’ll begin to see your worries slowly dissipate and that you have more mental space for positive thoughts. Once your mental health is in a better place, you’ll feel able to tackle anything.

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Traumatic Brain Injuries

Traumatic brain injury affects a high number of young adults and their hospitalization is still a significant public challenge. During neuronal damage a complex series of mechanisms becomes activated. Energy failure leads to calcium overload, depolarization of neurons and release of neurotransmitters with consecutive excitotoxicity, induced through overstimulation from excitatory receptors like NMDA receptor.

Injured neuronal tissue releases pro-inflammatory cytokines leading to migration of inflammatory cells to the damaged site and inflammation.  Cannabinoids (CBD) positively affect cellular and molecular processes during ischemic or traumatic brain injury and were shown to be protective mostly via microglial cells.

The number of damaged neurons was significantly reduced after treatment with endocannabinoids, like N-arachidonoyl dopamine, (2-AG) or PEA associated with altered microglial cell number.  2-AG was shown to induce protection after neuronal lesion and to reduce the amount of tumor necrosis factor α released from LPS activated microglial cells.

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What CBD oil is good for

If you follow cannabis news, you’re bound to have learned about a slew of conditions CBD oil is good for, including chronic pain and anxiety. But there are other uses that you may not have heard of yet.

Quitting smoking is one of the most difficult tasks for someone with a habit. Now anecdotal evidence shows that CBD can help not only with the depression and anxiety associated with quitting, but if you use a CBD pen in lieu of a cigarette or nicotine vape pen, the hand to mouth motion helps with that part of the addiction. Many people trying not to smoke find that they don’t know what to do with their hands during times when they crave a cigarette or e-cig, so a CBD vape pen is a perfect solution on many levels.

Did you know that CBD may have an effect on high blood pressure? Though you are always advised to talk to your doctor about treatments and to not stop any other treatment plans, adding CBD oil to your list of supplements couldn’t hurt. It is an innocuous component of the cannabis plant and has no psychoactive properties whatsoever when under the 0.3 percent THC mark. The fact that CBD also combats anxiety means that you shouldn’t be nervous to add it to your daily regime.

Talk to a medical consultant at True Natural Oils about dosages, milligrams and delivery systems. 

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CBD Helps!

CBD continues to be a constant in helping people through this uncertain time. This is precisely why CBD stores should be considered essential: If hemp and CBD products can be sold in other businesses classified as critical, the government must recognize on some level that access to CBD is essential. Still others pointed to the inconsistencies between how marijuana and alcohol have been treated under quarantine in comparison to CBD. If liquor and marijuana are considered essential, why isn’t CBD?

Consumers rely on CBD for everyday wellness and there are dozens of stories from CBD consumers whose health and well-being deteriorate markedly when they do not have access to their daily CBD regimen.

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True Natural Oils is Striving to Move Forward in Development

True Natural Oils is Striving to Move Forward in Development

The well-known saying for those hawking baseball scorecards might be just as appropriate in the fledgling CBD category. With more and more players entering the marketplace and many predicting that the category is finally ready to explode in sales, retailers may need a scorecard to know who the players are in the marketplace.

According to Boulder, Colo.-based BDS Analytics and Market Research, the collective market for CBD sales, which includes cosmetics, health products, food and beverage, pet products, skin care, and pharmaceuticals, is expected to exceed $20 billion in the United States by 2024.

We at True Natural Oils still are waiting for the Food and Drug Administration & develop regulations related to CBD in food and dietary supplements. The FDA maintains that there is a lack of scientific information supporting the use of CBD in food, and also noted that the agency is continuing to explore pathways for various types of CBD products to be marketed.

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Daily Regimens

Increasingly, patients are asking about or have already begun to add CBD to their daily regimens. What evidence is there for the efficacy of CBD?

Small trials in humans have examined the use of high-dose CBD (typically 300 to 1,000 mg per day, taken orally) in social anxiety in a simulated public speaking model (Bergamaschi et al., 2011; Zuardi et al., 2017).

Eating disorders are another area of interest, as the endocannabinoid system is a key regulator of appetite, but have not been examined in clinical trials. Finally, the antidepressant potential of CBD (possibly due to 5HT1A agonism, similar to some antidepressant medications) has been explored in more clinical studies with impressive results in relieving anxiety.