Increasingly, patients are asking about or have already begun to add CBD to their daily regimens. What evidence is there for the efficacy of CBD?
Small trials in humans have examined the use of high-dose CBD (typically 300 to 1,000 mg per day, taken orally) in social anxiety in a simulated public speaking model (Bergamaschi et al., 2011; Zuardi et al., 2017).
Eating disorders are another area of interest, as the endocannabinoid system is a key regulator of appetite, but have not been examined in clinical trials. Finally, the antidepressant potential of CBD (possibly due to 5HT1A agonism, similar to some antidepressant medications) has been explored in more clinical studies with impressive results in relieving anxiety.
