Tag: inflammation

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FAQ: What is the Relationship Between CBD & Autoimmune disorders?

Autoimmune Diseases such as: Lupus, Psoriasis, Type 1 Diabetes, Rheumatoid Arthritis, Inflammatory Bowel Disease, etc. have shown to be linked to stress. For example, in this study citing a higher incidence of autoimmune diseases among people who were previously diagnosed with stress-related disorders. Another paper publishes:

“Physical and psychological stress has been implicated in the development of autoimmune disease, since numerous animal and human studies demonstrated the effect of sundry stressors on immune function. Moreover, many retrospective studies found that a high proportion (up to 80%) of patients reported uncommon emotional stress before disease onset.

It is presumed that the stress-triggered neuroendocrine hormones lead to immune dysregulation, which ultimately results in autoimmune disease, by altering or amplifying cytokine [inflammatory response] production. The treatment of autoimmune disease should thus include stress management and behavioral intervention to prevent stress-related immune imbalance. “

Because of CBD’s ability to combat stress levels (see previous blog post), it provides as a preventative measure and potential therapy for Autoimmune Disorders as a stress management tool.

**These statements have not been evaluated by the food and drug administration (FDA). These products are not intended to diagnose, treat, cure or prevent any disease. The information is not medical advice, and should not be treated as such. 

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FAQ: How can CBD help my Stress Levels?

Modern-day science continues to show the link between Stress & Disease. Stress can be defined as any experience that causes tension, whether that be physical, psychological, or emotional- and especially if it sets off the “fight or flight” response – during which the adrenal gland releases adrenaline, leading to rapid pulse and breathing, and increased blood pressure).

“Chronic stress result [in] failures of homeostasis, [and] thus lead to various diseases such as atherosclerosis, non-alcoholic fatty liver disease (NAFLD) and depression. However, while 75%–90% of human diseases is related to the activation of stress system, the common pathways between stress exposure and pathophysiological processes underlying disease is still debatable.

Chronic inflammation is an essential component of chronic diseases. Additionally, accumulating evidence suggested that excessive inflammation plays critical roles in the pathophysiology of the stress-related diseases, yet the basis for this connection is not fully understood.” this paper publishes.

In previous blog posts, we have spoken widely about CBD’s potential in regulating inflammation and returning the body to homeostasis. We have even shown how CBD acts in a similar way as antidepressants as it works on the serotonin (5HT)1a receptor. Serotonin deficiency is associated with depression and other psychiatric disorders, and it is likely that the effects CBD has on mood and anxiety are related to this interaction.

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FAQ: Can CBD help with Skin Cancer?

The potential role of cannabinoids (CBD, CBG, etc) as antitumoral drugs is being explored in relation to the inflammatory component of skin cancer.

In vivo and in vitro studies that employed either phyto-, endo-, or synthetic cannabinoids show promise in topical treatment of Skin Cancer.

Cannabinoids are regarded with growing interest as eligible drugs in the treatment of skin inflammatory conditions with potential anticancer effects.

Topical CBD was also found effective in alleviating the symptoms of the following conditions: oxidative stress on dermal cells, skin conditions characterized by inflammation and keratin disorders, such as eczema or atopic dermatitis, wound healing, pain & muscle relief, itch (pruritis), Acne/Seborrhea, modulation of hair growth, skin & hair pigmentation, oral care, and other skin disorders such as antibiotic-resistant skin infections, cutaneous malignancies such as Melanoma, and Psoriatic Plaques.

Many studies currently report these effects, and the readiness in monitoring of effects and the facility of topical application may contribute to the growing support of the use of these substances. Not medical advice.

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FAQ: Can CBD affect my Heart Health & Blood Pressure?

The Month of February is all about Hearts. It is designated as Heart Health Month in the US, a time when all people can focus on their cardiovascular health.

Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide. They have a set of characteristic molecular components, such as a proinflammatory profile present in heart failure (HF), diabetic cardiomyopathy, and autoimmune myocarditis.

All of these molecular components associated with diverse CVDs can be modulated with Cannabinoid administration. Of particular interest of the Cannabinoids present in Cannabis, which is also produced within our bodies, has been CBD.

CBD is a potent anti-inflammatory and reduces the production of reactive oxygen and nitrogen species, thus resulting in reduced tissue injury. Such effects can be taken advantage of in varied diseases, such as cardiovascular and neurodegenerative diseases, cancer, pain, obesity, and metabolic syndrome.

Hypertension, or high blood pressure, is often called the ‘silent killer’ because most people who have it don’t have any symptoms. This can be a scary notion if we let it be, but we can also choose to take care of our bodies by making healthy choices to maintain our overall wellness.

A recent 2017 study on cardiac parameters in healthy males showed that subjects who had taken CBD, as opposed to a placebo, experienced lower blood pressure when exposed to stress.

In a 2009 study on rats, they were subjected to stressful situations, which in turn increased their heart rate and blood pressure. When the rats were then given a dose of CBD, their blood pressure and heart rate lowered.

It is proven high blood pressure can lead to stroke, heart attack, vision loss and kidney disease. However, we have now seen how CBD can be of great value as a cardioprotective agent due to its potent antioxidant and anti-inflammatory properties. 

As advocates in the CBD industry, our team is pleased to see many clinical studies employing the use of CBD as potential treatments of such destructive diseases. We also know encourage our community to remember that CBD is not a cure-all, though it can help. A balanced diet, mindset, and lifestyle are just as important in maintaining a healthy body and a health heart.

Thank you for letting us share this information with you. As always, this is not Medical Advice. Consult your trusted health professional, especially if you are on any prescribed medication.

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FAQ: Is CBD Effective Topically?

CBD topical application is considered the latest breakthrough in managing joint pain and inflammation. Together with its highly effective pain relieving properties, it possesses systemic absorption as well. ⁣

⁣CBD is absorbed through the skin where it binds to the body’s own CB2 receptors. Once it connects with these receptors, CBD has a pain relieving and anti- inflammatory effect on the body at the site of application.⁣

While CBD is popping up in many topical products, it’s not the only phyto-chemical within the cannabis plant to pay attention to. There are a lot of beneficial cannabinoids within cannabis, and our body has an entire system that regulates them. All of this comes into play when you slather the plant’s broad or full spectrum extracts on your skin.⁣ For example, THC has been shown to be 20 times more anti-inflammatory than aspirin and 2 times more anti-inflammatory than hydrocortisone.

The spectrum of cannabinoids work in concert more efficiently and effectively on these receptors than one on its own—hence it’s good to look for the whole plant’s extract infused with the plant’s helpful terpenes such as our True Natural Oils lotion or Golden Bee Hemp Pain Salve available here.

Topical CBD was also found effective in alleviating the symptoms of the following conditions: oxidative stress on dermal cells, skin conditions characterized by inflammation and keratin disorders, such as eczema or atopic dermatitis, wound healing, pain & muscle relief, itch (pruritis), Acne/Seborrhea, modulation of hair growth, skin & hair pigmentation, oral care, and other skin disorders such as antibiotic-resistant skin infections, cutaneous malignancies such as Melanoma, and Psoriatic Plaques.

In terms of Arthriits, one animal study from the European Journal of Pain reports CBD “significantly reduced” joint swelling/inflammation and pain from to arthritis when applied to skin. Additionally, CBD it is even being recommended by the Arthritis Foundation.

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FAQ: What is the Relationship Between Inflammation & CBD

Cannabis affects the body because its bioactive compounds bind to and activate tiny receptors encoded by our genes.

The brain and nervous system contain a different set of receptors (CB1) than the receptors used primarily in our immune system/inflammation (CB2).

Because CB2 activation dampens inflammatory responses, it has the potential to serve as a molecular target for diminishing inflammation linked to pathogenic disorders such as MS, ischemic/perfusion injury following an induced stroke, rheumatoid arthritis, inflammatory bowel disease and osteoporosis pain. (Centonze et. al 2007) .

Neuroinflammation is key to both autoimmune disorders (multiple sclerosis, lupus, psoriasis, etc) and Neurodegenerative diseases (Alzheimer’s, Parkinson’s, Huntington’s, etc) (Wolf Tauber, and Ullrich 2008; Pryce, Jackson and Baker 2008).

Disclaimer: not medical advice. These products are not approved by the FDA to treat, diagnose, or cure any disease.

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FAQ: “…But why would I even take CBD??”

Our Blog is an info-packed one but I wanted to give a brief overview for those looking for a quick answer to a basic question- “Why would I take CBD?”

The whole point of taking CBD Oil is to bring homeostasis (balance) back to the mind and body via the endocannabinoid system. Virtually every organism on Earth has an endocannabinoid system moderated by cannabinoids like CBD.

However, this complex network of receptors is commonly starving, and experiencing a “Cannabinoid Deficiency” in today’s environmental conditions.

Studies have shown the Endocannabinoid system ⁣is most abundant in the brain and immune system, and is responsible for important functions such as sleep, relaxation, inflammatory responses, cognitive ability and an endless list of other major functions within the body. So naturally when our system is experiencing this deficiency, these normal bodily functions can become out-of-wack per se.

If this has peaked your interest, read on! Or take a look at our reviews under each product and more on our Leave a Review page!

Additionally, if you have a specific question that you would like answered, shoot us an email at info@truenaturaloils.com !

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Cannabis May Reduce Deadly COVID-19 Lung Inflammation: Researchers Explain Why

As COVID-19 cases continue to rise, researchers have started to look for solutions in an unlikely place – the cannabis plant. Cannabis’ active compounds have a number of properties that make it appealing as a potential adjunct treatment for infections from the novel coronavirus, and recently scientists have begun looking at its potential for reducing susceptibility to the disease, and even discussed whether it could be used as an antiviral medication. 

This month, researchers from the University of Nebraska and the Texas Biomedical Research Institute are recommending more research into how cannabis-derived CBD might help treat dangerous lung inflammation from the novel coronavirus. The authors detailed the evidence for how cannabis’ anti-inflammatory powers may help in a peer reviewed article in this month’s issue of Brain, Behavior, and Immunity.

In the article, researchers explain that “recent reports have suggested that acute infection is associated with a cytokine superstorm, which contributes to the symptoms of fever, cough, muscle pain.” These extreme instances of inflammation can lead to severe pneumonia which clog up the lungs, make breathing difficult or impossible. So, one of the important strategies  that scientists are studying in the fight against COVID-19 is reducing inflammation.